Beginning at the Beginning

Time at the Beginning

Age consistency for the Universe today has been an important cosmological test. Even more powerful consistency tests at times as early as 10−32 sec lie ahead in the precision era of cosmology. I outline tests based upon cosmic microwave background (CMB) anisotropy, bigbang nucleosynthesis (BBN), particle dark matter, phase transitions, and inflation. The ultimate cosmic timescale – the fate of ...

Rehabilitation of Schizophrenia: At the End or in the Beginning?

The Majority of the long stay psychiatric patients who are in need of rehabilitation suffer from schizophrenia. Most of them enter the old age with this illness, and besides the consequences of schizophrenia, they are facing the deprivation and misery due to the old age. In contrast to the previous decades in which there was no effective treatment for schizophrenia, today with the immediate dia...

Thoughts at the beginning of the term

131 Thoughts at the beginning of the term The mission I was assigned, that of leading the biggest and the oldest school of medicine in Romania, is an honorable task, but, in the same time, it is very difficult. First, because we are going through a complex period, in which a change is requested and, most importantly is needed, but the reforms are, very often, misunderstood or inapplicable...

Looking at the End from the Beginning

Messenger RNA Degradation: Beginning at the End

The mechanisms responsible for mRNA decay in mammalian cells, and how specific sequence elements accelerate decay, are unknown. Recent work indicates that 'ARE' instability elements recruit the exosome to promote rapid 3'-to-5' degradation of the mRNA.